Take-Home Messages

• For the first time in literature, deep tissue implanted antenna radiation efficiency is accurately measured inside a tissue mimicking liquid phantom using a Reverberation Chamber (RC) technique.
• Although the radiation efficiency of a deep tissue implanted antenna can be extremely low (< 0.1%), this work shows how the RC technique can be used if care is taken to ensure that the feed cable does not significantly radiate, for example by routing the cable through the bulk of the tissue mimicking phantom.
• This work is relevant to any biomedical application or solution that is based on active implants that employ UHF radio communications or power transfer since in-situ radiation efficiency is the key design metric for such antennas and is core to the system link budget.
• In addition to establishing a method of efficiently and effectively measure implant antenna efficiency, something that is avoided in most published research papers, this work shows that significant errors are introduced when the antenna under test feed cable is not deeply inserted in the tissue phantom.

Take-Home Messages

• For the first time, detailed cardiophysiological and metrological causes of the diversity of measured heartbeat curves by continuous wave radar systems are presented as well as the possibility to measure locally specific pulse wave curves called sphygmograms.
• The measurement spot on the human body, the cutoff frequencies of the applied band pass filter, the antenna characteristics as well as the distance between antenna and target contribute to the signal shape of the measured heartbeat curves.
• Radar based locally specific pulse wave detection enables novel, contactless, cardiophysiological investigations for medical diagnostics.
• The causes of the diversity of published heartbeat curves are researched by investigating the cardiovascular system and the metrological influences on the measured signal shapes. Hereby, it is shown that adjusted filter characteristics and an appropriate distance between antenna and target enable radar based measurements of locally specific and medically relevant sphygmograms.
• The presented measurements were verified by a laser sensor as gold standard and medically substantiated by cardiophysiological researchers.

Take-Home Messages

• We propose a novel channel for supporting high data rate microwave communication by using the fat tissue.
• For up to 10 cm long fat tissue channel, we were able to achieve approximately 96 % data packet receptionwith a path loss of 1 dB and 2 dB at 10 mm in both phantom and ex-vivo environments, respectively.
• This work can be used in body area network, sensors application, and man-machine interfaces.
• Microwave communication through fat tissues was not known before. This work was successfully able todemonstrate data packet transmission through the porcine fat tissue.
• Through this study, we were able to show that the transmission loss (dB) in the muscle layer is more than twofoldof the transmission loss (dB) through the fat layer.

Take-Home Messages

• An innovative multi-frequency hyperthermia treatment planning strategy addressing the limitingclinical need represented by minimizing undesired heating is presented.
• This multi-frequency planning strategy, mf-FOCO, based on a convex programming problem, ensurea safe and efficient outcome of the treatment.
• The targeted medical application is hyperthermia treatment planning.
• Preliminary results confirmed the possibility of counteracting undesired heating exploiting multifrequencyapplicator while enforcing a patient-specific mask.

Take-Home Messages

• In this work, the detectability of African trypanosome parasites through passive resonant thin film sensing isexamined for the first time, providing the basis for a novel approach to fast pathogen screening tests targetingHuman African Trypanosomiasis (HAT).
• Cell-film sensitivity of asymmetric double-split rings is evaluated in simulation over different gap and filmconfigurations, using the material characterization presented in the original conference paper as a data basis.
• Simulation results are verified using phantom material and actual trypanosome parasites in pure form, whilealso examining the influence of varying dielectric contrast to dry cell buffer residue.
• The observed significant and rapid detectability of pure trypanosome parasites as a bulk material using planarresonators is a very important intermediate result on the way to a surface-functionalized parasite sensor, whichachieves high selectivity by use of RNA-based, highly affine and parasite-specific aptamer coatings.
• In ongoing research, we hope to achieve a sensor design which can immediately detect parasite presence in abarely pre-treated patient fluid sample based on the selection function of the aptamer, but possibly also byspectroscopic recognition of the cell itself if an individual spectral feature can be found in future work.

Take-Home Messages

• The level of MRI coil detuning and blocking is strongly dependent on the resistance of the control device which can change due to device heating
• More robust circuitry and understanding of both the electrical and thermal operation of the devices (and their interplay) will lead to more reliable MR instrumentation.
• The targeted medical application is MRI receive coil detuning/blocking circuits to protect the patient and the sensitive electronics in the presence of the high power slice-select pulse.
• The ability to model the control device’s thermal characteristics will lead to improved understanding of circuit operation, aid in the selection of control device for the specific MR application, and will lead to more reliable MRI instrumentation.