Determining the Position and Orientation of In-body Medical Instruments Using Near-Field Magnetic Field Mapping
Vedat Cavlu, Paul Brennan.
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The permanent magnet fails due to low power, and static current source requires relatively high power source. The RF field source requires high frequencies to get enough precision, which undergoes high attenuation in the body. At low frequency, when the distance between the source and the receiver array is shorter than the wavelength, the far field assumption fails for localization methods. Therefore, we propose a novel method of mapping the magnetic field vector in the near field region, with which wavelength independent localization is done. We did extensive MATLAB and CST Microwave simulations followed by practical experiments. The proposed method has achieved localization accuracy of less than 1 cm in Y-Z plane, 2 cm in depth (in X-axis) and the maximum orientation error remained 10° in 3-D.
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- This research aims to solve the issue with localization with near field of electromagnetism and in the lossy human tissues.
- The results show that, the position of in-body medical instrument can be determined within 1 cm and predict the orientation with error of maximum 10 degree.
- The proposed method is a novel way to determine location and orientation of an in-body medical-instrument.
- High accuracy localization in the challenging near field with relatively low frequency.
- This method can be performed from DC to up to frequencies that goes through the human tissues with negligible losses.
Impact of Electrode Structure on RF-induced Heating for an AIMD Implanted Lead in a 1.5-Tesla MRI System
Rui Yang, Jianfeng Zheng, Yu Wang, Ran Guo, Wolfgang Kainz, Ji Chen.
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It is shown that increasing the size of lead electrode reduces the SAR distribution and temperature rise near the electrode. Our results indicate that a larger electrode size will reduce the magnitudes of the lead transfer function, and subsequently reduces the heating effect near the electrode. Both numerical simulations and experimental measurements were performed to verify the effectiveness of a large electrode in mitigating the RF-induced heating.
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- Sophisticated electromagnetic modeling and experiments were performed to assess the effect of the electrode structure on the radio frequency (RF) -induced heating.
- For this case study, we found that increasing the electrode size tends to reduce the magnitude of the lead transfer function, subsequently reducing the RF-induced heating near the electrode.
- To present a lead electrode which can reduce the RF-induced heating for active implantable medical devices (AIMDs) under magnetic resonance imaging (MRI).
- We could demonstrate that the electrode structure of the lead tip has an impact on the MRI RF-induced heating of the AIMDs.
- Both simulations and experiments demonstrate that increasing the electrode size reduces the RF-induced heating for an implanted lead during MRI scanning.
Feasibility Study of Hydration Monitoring using Microwaves Part 2: Measurements of Athletes
David Christopher Garrett, Jared R. Fletcher, David B. Hogan, Tak Shing Fung, Elise Fear.
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Extremity microwave measurement is a promising method for ongoing hydration monitoring, owing to the inherent differences in dielectric properties with varying tissue water content. This paper reports on a feasibility study of textit{in vivo} hydration assessment using microwave measurements in athletes undergoing acute water loss during exercise. We developed and then tested a system for performing reliable microwave property estimation at the forearm. This system was used to measure hydration status in varsity wrestlers before and after a training session. A relationship between estimated permittivity and body weight change due to water loss was found, showing promise for the use of microwaves to assess hydration status. No significant relationship with attenuation was found. A novel method of assessing changes in hydration status is described, which may be of practical use for athletes in guiding fluid replacement during and after exercise.
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- Microwaves are inherently sensitive to water content, and may therefore provide a clinically-relevant method of noninvasive hydration monitoring.
- This study presents a validation study of microwave techniques for hydration assessment in athletes by performing measurements prior to and following acute water loss due to exercise.
- We find changes in estimated permittivity with water loss, but no relationship with measured attenuation.
- Athletes may find applications of this technique in guiding fluid replacement for maximal performance and safety during exercise and recovery.
Feasibility Study of Hydration Monitoring using Microwaves Part 1: A Model of Microwave Property Changes with Dehydration
David Christopher Garrett, Elise Fear.
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However, existing assessment techniques lack the accuracy and/or convenience for ongoing monitoring, motivating the development of novel methods. We propose using low-power microwave measurements (2-12 GHz) at the extremities to monitor human hydration, relying on the strong relationship between dielectric properties of tissues and water content. Electromagnetic simulations of realistic models are used to explore changes in microwave signals transmitted through the forearm to changes in hydration. Tissue properties are adjusted according to expected changes in water content, and average dielectric properties are estimated from signals transmitted through the arm by ultra-wideband antennas placed in contact with the tissues. A causal relationship between weight loss due to water loss and dielectric permittivity is found in human simulation models. Little relationship is found with conductivity. The theoretical groundwork for hydration assessment with microwaves is developed through a model which relates changes in total body water content with changes in microwave properties at the extremities. This model could be useful for monitoring hydration in at-risk populations such as older adults and athletes.
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- Microwave techniques may provide a convenient method of noninvasive hydration assessment due to the strong relationship between dielectric properties and water content in biological tissues.
- The feasibility of microwave hydration assessment is demonstrated through a physiologically-driven framework for modeling changes in microwave properties at the extremities during dehydration.
- Our target application is hydration assessment in athletes and older adults due to the elevated risk of dehydration from their activity, environment, and/or physiological changes.
- It is found that permittivity is a more sensitive metric than conductivity when assessing water-loss dehydration.
- The modeling techniques developed in this paper provide the framework for interpreting in vivo experimental measurements in the context of hydration assessment.
A Survey on Electromagnetic Risk Assessment and Evaluation Mechanism for Future Wireless Communication Systems
Muhammad Ali Jamshed, Fabien Heliot, Tim Brown.
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Similarly, the multiplication of future connected devices,e.g. internet of things(IoT)devices, will also contribute to an increase in EMF exposure. This paper provides a detailed survey relating to the potential health hazards linked with EMF exposure and the different metrics that are currently used for evaluating,limiting and mitigating the effects of this type of exposure on the general public. This paper also reviews the possible impacts of new wireless technologies on EMF exposure and proposes some novel research directions for updating the EMF exposure evaluation framework and addressing these impacts in future wireless communication systems. For instance, the impact of mmWave or massive-MIMO/beamforming on EMF exposure has yet to be fully understood and included in the exposure evaluation framework.
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- This paper provides a detailed survey related to the possible health hazards linked with EMF exposure based on what empirical studies suggest and the different metrics that are currently used for evaluating, limiting and mitigating the effects of this type of exposure on the general public.
- Brain tumour is still the main cause of concerns, which may be related to the extensive use of wireless devices, even though the effects of EMF exposure is now being investigated in other parts of the body (e.g. eyes, reproductive system). Moreover, some studies advocate a modification of the guidelines to better take into account the duration of exposure (i.e. long-term exposure).
- Generic/composite metrics (based on existing metrics) have recently been designed to better evaluate the exposure of large geographical area. A generic metric for measuring the individual exposure would also be of interest.
- Key 5G enabling technologies, such as densification, massive MIMO, and mmWave, will surely have an impact on the ambient level of EMF exposure in the near future, but they will also provide new opportunities to reduce it, e.g. context-aware beamforming or low exposure spatial modulation schemes.
Sensitivity Analysis for Ultra-wideband 2-port Impedance Spectroscopy of a Live Cell
Xiao Ma ; Xiaotian Du, Lei Li, Hang Li, Xuanhong Cheng, James Hwang.
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The sensitivity analysis validated our previous empirical observation that the insertion loss of a series-trapped cell and the return loss of a shunt-trapped cell were most sensitive to the cell impedance. Additionally, the membrane resistance and cytoplasm capacitance were most sensitive to low- and high-frequency scattering parameters, respectively. In the future, the analysis can be used to optimize the test setup and protocol for fast, compact and label-free characterization of a cell at the subcelluar level.
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- Live cells were characterized individually in a fast, compact and label-free manner, and the dynamic range of the impedance spectroscopy was greatly increased by 2-port instead of 1-port measurements.
- A lumped equivalent circuit of nondispersive resistances and capacitances was found sufficient to explain the impedance spectrum of a cell between 9 kHz to 9 GHz, and the sensitivity of the cell impedance to microwave scattering (S) parameters was analyzed for the first time.
- The equivalent circuit parameters were found the most sensitive to the insertion loss of a series-trapped cell and the return loss of a shunt-trapped cell on the coplanar waveguide.
- The equivalent circuit parameters could be reliably extracted because low-frequency S-parameters were mainly governed by the membrane resistance, high-frequency S-parameters were mainly governed by the cytoplasm capacitance, and intermediate-frequency S-parameters were mainly governed by the membrane capacitance and cytoplasm resistance.
- The theory of ultrawideband impedance spectroscopy was carefully derived and documented for the first time.