Magnetic Transceiver Beamforming for A 2 × 2 Magnetic Resonance Charging System
Xiaoqing Liu, Bingqing Mei, Xiaodong Wang, Zhigang Wen
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The formulated problem is nonconvex and we propose an efficient iterative solution by solving a series of geometric programs that approximate the original problem. Both numerical results and simulation results in COMSOL model are provided to demonstrate the effectiveness of the proposed biomedical wearable system and optimization algorithm.
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- This paper proposes a 2×2 magnetic resonance charging system considering both magnetic transmit beamforming and receive beamforming for charging wearable medical devices.
- Both numerical results and simulation results in COMSOL model are provided to demonstrate the effectiveness of the proposed system and optimization algorithm.
- The target medical applications are wearable medical devices using for Alzheimer’s disease, ergonomics, rehabilitation and neurology which are inconvenient or sometimes infeasible to replace or change batteries for the elderly or patients.
- Such a magnetic resonance charging system provides a promising way to make wearable medical devices permanently unplugged.
Transmission Line Model Of An Implemented Insulated Cable For Magnetic Resonance Imaging Radiofrequency Hazard Evaluation
Alexia Missoffe, Julie Kabil, IADI, Pierre-Andre Vuissoz, Jacques Felblinger
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The equivalence between the models is shown through a finite difference model and a new analytical formula for the transfer function as a function of transmission line parameters. First, the possibility of modeling an insulated cable with a transmission line model was analyzed through full-wave numerical simulations. The assumption of a transmission line model underlying the transfer function model was shown to be right for a simple cable embedded in tissue imitating gel and the transmission line parameters extracted from this analysis were consistent with analytical formulas derived from the laws of physics. The transmission line model predictions were first compared to experimental and simulated data of the cable transfer function and then, to experimental and simulated data of the resonant behavior as a function of length of cables with different termination conditions. The measured and simulated transfer functions fit perfectly a transmission line model with an analytical expression of the propagating constant. The transmission line model extracted from the transfer function allows to predict the resonant behavior of two cables with different termination conditions
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- An insulated cable implanted in a lossy material and submitted to a radiated radiofrequency field can be modeled by a modified transmission line with a distributed excitation along the line.
- This model gives a better physical insight into the problem of the compatibility of implanted cables in Magnetic Resonance Imaging (MRI) such as pacemaker, defibrillator or neurostimulator leads.
- This work shows the equivalence between the transfer function model usually used to model the interaction of an implanted lead with the radiofrequency field of MRI and the modified transmission line model.
- An idea that can be derived from this model is to reduce the heating at the electrode of an implanted lead by creating a big reflection coefficient before the end of the lead using a multi-section approach
Magnetoresistive Biosensors for On-Chip Detection and Localisation of Paramagnetic Particles
Zhaochen Yin, Edoardo Bonizzoni, Hadi Heidari
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A new calibration and localisation algorithm has been coded and implemented. In order to generate the required homogenous magnetic field, a custom 3D printed Hallbach cylinder has been simulated and characterised. The system includes sensory and electronic boards to collect the data and to transfer them to a computing server. The experimental results are displayed in a visual interface. Ferrofluid is used to model and simulate the magnetic field change of the cell. This paper demonstrates a 4×4 sensors array and provides a step towards the miniaturised on-chip magnetoresistive based cell detection and localisation for portable diagnostics applications.
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- This paper presents the design and the implementation of an on-chip magnetoresistive sensors array for cell detection and localisation. Giant magnetoresistance (GMR) sensors have been used due to their high sensitivity and resolution.
- A novel calibration and localisation algorithm has been coded and implemented. In order to generate the required homogenous magnetic field, a custom 3D printed Hallbach cylinder has been simulated and characterised.
- Sensory chips could detect an average magnetic sensitivity of 2 V/T at room temperature.
- The ferrofluid and a customised 3D printed Halbach cylinder were employed to simulate the magnetic field change in the cell.
- The implemented algorithm helps in achieving high sensitivity and positioning speed, also thanks to an accurate calibration of the GMR sensors.
Characterisation of the Dielectric Properties of the Bladder over the Microwave Range
Emily Porter, Saqib Salahuddin, Alessandra La Gioia, Adnan Elahi, Atif Shahzad, Arun Kumar, David Kilroy, M. O’Halloran,
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A number of such technologies have been proposed to target the diagnosis or treatment of bladder conditions, including urinary incontinence and bladder cancer. However, available dielectric data for the bladder is extremely limited in scope and has not been updated in line with modern knowledge, including best practices in measurement procedures to reduce the impact of confounders, along with improved reporting of experimental metadata. For these reasons, in this work we present a study of dielectric measurements on the bladder of freshly excised bovine and porcine tissues over the microwave frequency range. We examine the properties of the inside and outside of the bladder wall, and carefully control and record confounders during the measurements. The obtained data is analysed in terms of confounders (temperature, time from excision, inter-species differences), and compared to data from the literature. The resulting dataset, composed of 52 measurements from 10 animals, provides a thorough and quantitative understanding of the dielectric properties of the bladder. The results of this study will benefit the development of related electromagnetic medical technologies, and thereby positively impact on patient care over the long-term.
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- Accurate knowledge of the dielectric properties of tissues is the basis for electromagnetic (EM) medical device design, development, and optimisation, and therefore, lack of knowledge on the dielectric properties of the bladder is a stumbling block for the application of bladder-related technologies, including EM therapeutic and diagnostic tools.
- This study provides a critical, anatomy-informed dielectric study of the properties of the bladder.
- Through a large number of tissue measurements, this study examines for the first time the impact of the dielectric properties of the bladder in light of common measurement confounders (time from excision, temperature), and uniquely examines the properties of both the inside and the outside of the bladder wall.
- This study provides reliable dielectric data of the bladder over the microwave frequency range, and fitted dielectric models, that can be used to support the design of bladder-related medical technologies.
- This study has been performed in line with modern best practices standards for the reporting of experimental metadata along with experimental data, and the data and metadata will be made openly available online.
A Miniaturized Four-Element MIMO Antenna with EBG for Implantable Medical Devices
Yi Fan, JinHong Huang, TianHai Chang, Xiongying Liu.
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A cross-shaped slot etched in the radiator, a branch extending on the conductor ground, and a pair of electromagnetic band gaps (EBGs) are integrated to achieve high isolation. The proposed MIMO antenna has the compact dimensions of 18.5 mm × 18.5 mm × 1.27 mm. The simula-tion in the three-layer phantom indicates that the impedance matching is good with a bandwidth of 18.64% (2.14-2.58 GHz) and a maximum gain of -15.18 dBi and the mutual coupling is reduced to less than -15.99 dB at the ISM band. An ex-vivo test was implemented in a fresh pork slab and the measurement results are well matched with the simulation ones. Health safety considerations and link budget are discussed to validate the antenna’s availability in biomedical telemetry, and the envelope correlation coefficient is computed, illustrating the high independence between antenna elements.
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- In MIMO wireless systems, multiple antenna elements are adopted to work as transmitter and receiver to improve capacity such as the enhancement in the data transmission rates of high resolution images from the capsule to outside base station/gateway.
- The proposed four-element implantable MIMO antenna features a wide impedance bandwidth of 18.64% (2.14–2.58 GHz) with a maximum gain of –15.18 dBi, and has the compact dimensions of 18.5 mm × 18.5 mm × 1.27 mm. The mutual coupling between different antenna elements is less than –15.99 dB.
- The ex-vivo measured results illustrate a merit agreement with the simulated ones in a three-layer phantom. The radiation characteristic of the designed antenna follows the healthy protection standards, and the performance of diversity and far-field link budget indicates merit channels characteristics.
Magnetic and Thermal Characterization of Core-Shell Fe-oxide@SiO2Nanoparticles for Hyperthermia Applications
Gabriele Barrera, Marco Coïsson, Federica Celegato, Elena Sonia Olivetti, Luca Martino, Ivana Miletto, Paola Tiberto.
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Their size remains therefore as small as possible, while still displaying significant hysteresis losses in dynamic conditions (electromagnetic fields up to 48 kA/m at 100 kHz). Static loops measured by vibrating sample magnetometry and dynamic loops measured by a custom B-H tracer are used to characterize the particles magnetic properties, as well as a custom-built, fully modelled, hyperthermia setup. The specific absorption rate is obtained either from static and dynamic loops areas, and from direct hyperthermia measurements. Dynamic loops are shown to be a good estimator of specific absorption rate values.
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- Core@shell Fe-oxide@SiO2 nanoparticles: a system for delivering heat selectively to cancer cells through an alternating electromagnetic field. This study provides a critical, anatomy-informed dielectric study of the properties of the bladder.
- The most effective heat transfer is obtained through a maximisation of the energy losses: a careful investigation of the nanoparticles system is required to comply with the constraints imposed by hyperthermia applications.
- An almost superparamagnetic system that minimises magnetostatic interactions (e.g. agglomeration) while keeping dynamic hysteresis losses for heat delivery.